Chandler

Joey famously shared an apartment with his best friend Chandler Bing. The two formed perhaps one of the most likeable and enduring television friendships in sitcom history. Their adventures included losing Ross's baby son on a bus, Chandler's dismay at Joey building an entertainment centre which was so big it covered both of their doors (during the construction of which Joey cut Chandler's door in half with a circular saw, which was not fixed for years), buying a chick and a duck (affectionately named 'The Chick and The Duck'), replacing their dining table with a foosball table, spending hours watching Baywatch and Chandler living in a box to prove how much their friendship means to him. A long-running gag depicted Joey and Chandler occasionally fighting with each other like an old married couple, with Chandler often assuming the wife role while Joey assumed the husband role, suggesting homosexual undertones in their friendship (this eventually ended when Chandler became permanently paired with Monica). The two "broke up" temporarily after Joey found success as Dr. Drake Ramoray, but soon moved back in together (after fooling the psychopathic replacement roommate Eddie into believing he had never lived with Chandler). In the final episode, Monica destroyed the foosball table (when the two couldn't bring themselves to do it to release the trapped Chick Jr. and Duck Jr.), before Chandler moved to the New York suburbs to begin their new family. However, Chandler and Monica made it clear that their new home would have a specially designated "Joey room".

When Chandler moved out to pursue a relationship with Monica, Joey was joined by Janine (Elle MacPherson). He formed a stronger bond with Rachel Green during her pregnancy by Ross Geller. He eventually fell in love with Rachel and dated her for a time; however, nothing came of it and the two returned to being just good friends. By the series' finale, Rachel and Ross resumed their romance.

Joey is perhaps the most loyal of the friends. As he said in The One with the Jellyfish, "If I had to, I'd pee on any one of you!", referring to the awkward act of urinating on a jellyfish wound to subside pain (although he actually could not urinate on Monica's wound, due to getting "stage fright"). In one episode, when Joey believed Phoebe to be pregnant, he proposed marriage, claiming the world is too scary for a single mother alone. However, when it was revealed that it was in fact Rachel who was pregnant, Joey proposed to Rachel, making the exact same speech and demanding the ring back from Phoebe. He also offered to stand up for Ross and Chandler when they were being bullied at Central Perk, and he allowed Monica to hire and fire him so as to prove to her employees that she was not a pushover. When he discovered that Monica and Chandler had developed a romantic relationship and they learned about it, he agreed to keep it a secret until the two were ready to reveal it to the rest of their group (although he was not above humiliating Monica by covering her and Chandler's affair up with the statement that he himself had slept with her in London). He also called Chandler moments after suspecting Monica of having an affair with a mystery male he had heard in her apartment (who in fact turned out to be Chandler. "I told you, you shouldn't have married someone so much hotter than you!"). He is also the only one that knew that Chandler is afraid of dogs (Chandler then says it to the other Friends and Joey warns him not to do it, because they were going to get mad) and that Ross doesn't like ice cream.

It is implied in the series that the other Friends think that Joey is immature, and Chandler even claims that he is responsible for Joey's well-being.

Joey's relationships with the other Friends have always been very friendly. He is best friends with Chandler, and Ross is a close second, if not tied. Rachel and the other women on the show have been the object of many unintentionally sexist comments on Joey's behalf, especially Monica. Chandler once put it, "Your long-standing offer to have sex with my wife is much appreciated." This statement fairly accurately summarizes his behavior around most women.

Notwithstanding this apparent boorishness, however, he always enjoyed a close relationship with Monica, Rachel and Phoebe.

Ironically, in the end of the series, Joey was the only Friend that ended up without a lover or a spouse (Ross and Rachel, Monica and Chandler, Phoebe and Mike), as he is the one that dated most women. He also is the only one to end up without any kind of children (Ross had Ben and Emma, Rachel had Emma, Phoebe had the triplets and Chandler and Monica had the adopted twins). Although in some times Joey had shown not to like children (when Rachel was going to say to Emma's father she was pregnant, she asked Joey how would he react if a girl told him he was going to have a baby, and he got really scared and started asking "Someone called? Was she blond and short?"), he also says he likes them and once he told he wanted to call his kid "The Hulk". Chandler kissed all the other 5 Friends, and Joey was the first that kissed him.

Joey has a close relationship with Rachel, also having been attracted to her twice in the series. Once his affection was unreturned in Season 8, once they actually dated in a later season. In many ways, Joey and Rachel are rather similar, both interested in material things, Joey a ladies' man and Rachel the 'guy magnet' of the three female Friends.

Joey has a close relationship with Phoebe. When she was a surrogate mother for her brother's triplets, he offered to eat no meat until the babies were born (Vegetarian Phoebe craved meat and he suggested that if he was a vegetarian, she "would be eating his animals, and no other animals would have to die"). Also, when the Friends realize that the group may have to split up, Phoebe and Rachel conspired to form a separate group by themselves, but Phoebe insists that Joey come to their new group as well. Phoebe's loyalty is proved again in "The One in Vegas, Part One", when she states that she could live in Las Vegas, since it has everything she needs, "Including Joey!" He in turn invites her to live in the thumb of his hand mansion in "The One in Vegas, Part Two". Phoebe also once says to her friends, "When the Revolution comes, I'll have to kill you all." After a moment's pause, she adds, "Not you, Joey." He seems very pleased about this. The two also try to meet once a month for dinner in order to discuss the other Friends.

Ex-Girlfriends: Angela Del Vecchio, Kate Miller, Ginger, Erika, Ursula Pamela Buffay, Katie, Charlie Wheeler, Janine Lecroix, Rachel Green